Keeping information in clipboard may be dangerous if you are copying something like credit card number or passwords so you can clear your clipboard by following steps.
1. Win+R or Start=>Run
2. Type clipbrd (This will open Clip Board)
3. Edit Menu => delete
Or
1. Go to C:\WINDOWS\system32
2. Run clipbrd.exe
3. Edit Menu => delete
There are too many free and paid softwares do clear clipboard with too many options.
But actually what i wanted is that when I paste the copied content at that time the clipboard should be cleared, that is paste the copied content only once, but could not find anything like that.